Quick summary - link to full text is below.
Mitochondrial dysfunction noted in individuals with chronic fatigue syndrome. Those with more severe dysfunction had more severe fatigue.
See an attached PDF of the actual article. While this is not a multiple sclerosis patient population - it does lend credence to theory that mitochondrial dysfunction has a role in the disabling fatigue in worsening MS.
My advice -- eat specifically for your mitochondria. Be sure you've got a rich source of B vitamins (mushrooms, dark green leafy vegetables), co-enzyme Q (wheat germ or organic liver), and antioxidants (intense colors, preferably some purple-black, red, and yellow-orange each day). Spending most of your calories each day on organic vegetables, fruit, seeds/ nuts is a great way to add to your micro-nutrient content.
The link below should get you to the article
Int J Clin Exp Med (2009) 2, 1-16
Chronic fatigue syndrome and mitochondrial dysfunction
Sarah Myhill1, Norman E. Booth2, John McLaren-Howard3
1Sarah Myhill Limited, Llangunllo, Knighton, Powys, Wales LD7 1SL, UK; 2Department of Physics and Mansfield College, University of Oxford, Oxford OX1 3RH, UK; 3Acumen, PO Box 129, Tiverton, Devon EX16 0AJ, UK